# Thermosensitive Gel Nasal Spray With Exosomes, Azelastine, and Interferon for Acute Phase of Chronic Sinusitis

> **NCT07635459** · EARLY_PHASE1 · NOT_YET_RECRUITING · sponsor: **The First Affiliated Hospital of Xinxiang Medical College** · enrollment: 108 (estimated)

## Conditions studied

- Chronic Rhinosinusitis Without Polyps

## Interventions

- **DRUG:** Exosomes, Azelastine, and Interferon alpha-2b
- **DRUG:** Azelastine and Interferon alpha-2b
- **DRUG:** Placebo Gel Matrix

## Key facts

- **NCT ID:** NCT07635459
- **Lead sponsor:** The First Affiliated Hospital of Xinxiang Medical College
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07-01
- **Primary completion:** 2027-06-30
- **Final completion:** 2027-06-30
- **Target enrollment:** 108 (ESTIMATED)
- **Last updated:** 2026-06-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07635459

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07635459, "Thermosensitive Gel Nasal Spray With Exosomes, Azelastine, and Interferon for Acute Phase of Chronic Sinusitis". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07635459. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*