# DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.

> **NCT07635563** · PHASE2 · RECRUITING · sponsor: **Incannex Healthcare Ltd** · enrollment: 120 (estimated)

## Conditions studied

- Obstructive Sleep Apnea (OSA)

## Interventions

- **DRUG:** IHL-42X: 2.5 mg dronabinol + 125 mg acetazolamide
- **DRUG:** IHL-42X: 5 mg dronabinol + 125 mg acetazolamide
- **DRUG:** IHL-42X: 7.5 mg dronabinol + 125 mg acetazolamide
- **DRUG:** IHL-42X: 2.5 mg dronabinol + 250 mg acetazolamide
- **DRUG:** IHL-42X: 5 mg dronabinol + 250 mg acetazolamide
- **DRUG:** IHL-42X: 7.5 mg dronabinol + 250 mg acetazolamide
- **DRUG:** IHL-42X: 2.5 mg dronabinol + 375 mg acetazolamide
- **DRUG:** IHL-42X: 5 mg dronabinol + 375 mg acetazolamide
- **DRUG:** IHL-42X: 7.5 mg dronabinol + 375 mg acetazolamide
- **DRUG:** Placebo: Negative control

## Key facts

- **NCT ID:** NCT07635563
- **Lead sponsor:** Incannex Healthcare Ltd
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-07-21
- **Primary completion:** 2027-04
- **Final completion:** 2027-05
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2026-09-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07635563

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07635563, "DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07635563. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*