# Intranasal Esketamine-dexmedetomidine Combination and Postpartum Depression

> **NCT07639099** · PHASE4 · NOT_YET_RECRUITING · sponsor: **Peking University First Hospital** · enrollment: 164 (estimated)

## Conditions studied

- Parturients
- Depressive Symptoms
- Esketamine
- Dexmedetomidine
- Intranasal Administration
- Postpartum Depression

## Interventions

- **DRUG:** Esketamine-dexmedetomidine combination
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07639099
- **Lead sponsor:** Peking University First Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-06
- **Primary completion:** 2029-10
- **Final completion:** 2029-12
- **Target enrollment:** 164 (ESTIMATED)
- **Last updated:** 2026-06-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07639099

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07639099, "Intranasal Esketamine-dexmedetomidine Combination and Postpartum Depression". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07639099. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*