# The Application of Locoregional Therapy Combined With Systemic Therapy in the Perioperative Period of Huge Hepatocellular Carcinoma: A Retrospective Cohort Study

> **NCT07639294** · — · COMPLETED · sponsor: **Tongji Hospital** · enrollment: 715 (actual)

## Conditions studied

- Huge Hepatocellular Carcinoma (HCC) (>10cm)

## Interventions

- **PROCEDURE:** hepatectomy without immune checkpoint inhibitors-based adjuvant therapy
- **PROCEDURE:** hepatectomy with immune checkpoint inhibitors-based adjuvant therapy
- **PROCEDURE:** neoadjuvant conversion therapy followed by surgery
- **DRUG:** Non-surgery

## Key facts

- **NCT ID:** NCT07639294
- **Lead sponsor:** Tongji Hospital
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2018-06-01
- **Primary completion:** 2025-12-31
- **Final completion:** 2025-12-31
- **Target enrollment:** 715 (ACTUAL)
- **Last updated:** 2026-06-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07639294

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07639294, "The Application of Locoregional Therapy Combined With Systemic Therapy in the Perioperative Period of Huge Hepatocellular Carcinoma: A Retrospective Cohort Study". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07639294. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*