# Safety and Efficacy Study of Collagenase CNT201 Injection for Treatment of Dupuytren's Contracture

> **NCT07640425** · PHASE1,PHASE2 · RECRUITING · sponsor: **CONNEXT** · enrollment: 60 (estimated)

## Conditions studied

- Dupuytren Contracture
- Dupuytren Disease of Finger

## Interventions

- **DRUG:** [Step1] CNT201 First-dose
- **DRUG:** [Step1] CNT201 Low-dose
- **DRUG:** [Step1] CNT201 Intermediate-dose
- **DRUG:** [Step1] CNT201 High-dose
- **DRUG:** [Step2] CNT201
- **DRUG:** [Step2] Placebo

## Key facts

- **NCT ID:** NCT07640425
- **Lead sponsor:** CONNEXT
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-07-23
- **Primary completion:** 2027-07-01
- **Final completion:** 2027-07-25
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2026-06-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07640425

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07640425, "Safety and Efficacy Study of Collagenase CNT201 Injection for Treatment of Dupuytren's Contracture". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07640425. Licensed CC0.

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