# Influence of Oral Probiotics on Anxiety and Depression in Adolescents After Non-cardiac and Non-gastrointestinal Surgeries: A Prospective, Double-blind, Placebo-controlled Study

> **NCT07640490** · EARLY_PHASE1 · COMPLETED · sponsor: **Henan Provincial People's Hospital** · enrollment: 150 (actual)

## Conditions studied

- Anxiety Depression

## Interventions

- **DRUG:** C Group
- **DRUG:** P Group

## Key facts

- **NCT ID:** NCT07640490
- **Lead sponsor:** Henan Provincial People's Hospital
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2025-08-02
- **Primary completion:** 2026-05-02
- **Final completion:** 2026-05-02
- **Target enrollment:** 150 (ACTUAL)
- **Last updated:** 2026-06-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07640490

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07640490, "Influence of Oral Probiotics on Anxiety and Depression in Adolescents After Non-cardiac and Non-gastrointestinal Surgeries: A Prospective, Double-blind, Placebo-controlled Study". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07640490. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*