# The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Non-inflatable Transoral Endoscopic Thyroid Surgery

> **NCT07641673** · NA · NOT_YET_RECRUITING · sponsor: **The Second Hospital of Anhui Medical University** · enrollment: 186 (estimated)

## Conditions studied

- Thyroidectomy
- Coughing Reflex

## Interventions

- **DRUG:** Esketamine（iv）
- **DRUG:** ESK spray
- **DRUG:** Normal Saline

## Key facts

- **NCT ID:** NCT07641673
- **Lead sponsor:** The Second Hospital of Anhui Medical University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-06
- **Primary completion:** 2027-05
- **Final completion:** 2027-09
- **Target enrollment:** 186 (ESTIMATED)
- **Last updated:** 2026-06-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07641673

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07641673, "The Effect of Esketamine on Cough Reflex During Tracheal Extubation in Patients Undergoing Non-inflatable Transoral Endoscopic Thyroid Surgery". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07641673. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*