# MRI-based Focal Intraprostatic Simultaneous Integrated Boost (SIB) Intensification With De-escalated Adaptive-risk SBRT for Patients With Low to Intermediate Risk Prostate Cancer

> **NCT07644598** · PHASE2 · RECRUITING · sponsor: **Georgetown University** · enrollment: 58 (estimated)

## Conditions studied

- Prostate Cancer
- Localized Prostate Carcinoma

## Interventions

- **RADIATION:** Microboost SBRT
- **RADIATION:** Whole gland de-escalation 30 Gy
- **RADIATION:** Whole gland de-escalation 35 Gy

## Key facts

- **NCT ID:** NCT07644598
- **Lead sponsor:** Georgetown University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-09
- **Primary completion:** 2028-01
- **Final completion:** 2035-01
- **Target enrollment:** 58 (ESTIMATED)
- **Last updated:** 2026-08-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07644598

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07644598, "MRI-based Focal Intraprostatic Simultaneous Integrated Boost (SIB) Intensification With De-escalated Adaptive-risk SBRT for Patients With Low to Intermediate Risk Prostate Cancer". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07644598. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*