# FH-WT1-E50 TCR T Cells With Azacitidine for the Treatment of Minimal Residual Disease Positive Acute Myeloid Leukemia

> **NCT07645469** · PHASE1 · RECRUITING · sponsor: **Fred Hutchinson Cancer Center** · enrollment: 9 (estimated)

## Conditions studied

- Acute Myeloid Leukemia

## Interventions

- **DRUG:** Autologous HLA-A*02:01-restricted CD4+/CD8+ Anti-WT1 TCR/CD8ab-expressing T-cells
- **DRUG:** Azacitidine
- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Bone Marrow Aspiration
- **PROCEDURE:** Bone Marrow Biopsy
- **PROCEDURE:** Chest Radiography
- **PROCEDURE:** Computed Tomography
- **PROCEDURE:** Echocardiography Test
- **PROCEDURE:** Lumbar Puncture
- **PROCEDURE:** Multigated Acquisition Scan
- **PROCEDURE:** Positron Emission Tomography

## Key facts

- **NCT ID:** NCT07645469
- **Lead sponsor:** Fred Hutchinson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-10-15
- **Primary completion:** 2030-07-19
- **Final completion:** 2030-07-19
- **Target enrollment:** 9 (ESTIMATED)
- **Last updated:** 2026-09-17

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07645469

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07645469, "FH-WT1-E50 TCR T Cells With Azacitidine for the Treatment of Minimal Residual Disease Positive Acute Myeloid Leukemia". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07645469. Licensed CC0.

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