# Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors

> **NCT07647068** · PHASE2 · NOT_YET_RECRUITING · sponsor: **Joal Beane** · enrollment: 59 (estimated)

## Conditions studied

- Locally Advanced Gastrointestinal Stromal Tumor
- Metastatic Gastrointestinal Stromal Tumor
- Recurrent Gastrointestinal Stromal Tumor
- Refractory Malignant Gastrointestinal Stromal Tumor
- Unresectable Malignant Gastrointestinal Stromal Tumor

## Interventions

- **BIOLOGICAL:** Aldesleukin
- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Chest Radiography
- **PROCEDURE:** Computed Tomography
- **DRUG:** Cyclophosphamide
- **PROCEDURE:** Echocardiography Test
- **BIOLOGICAL:** Filgrastim
- **DRUG:** Fludarabine
- **PROCEDURE:** Magnetic Resonance Imaging
- **PROCEDURE:** Multigated Acquisition Scan
- **PROCEDURE:** Positron Emission Tomography
- **PROCEDURE:** Surgical Procedure
- **BIOLOGICAL:** Tumor Infiltrating Lymphocyte Therapy

## Key facts

- **NCT ID:** NCT07647068
- **Lead sponsor:** Joal Beane
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-08-15
- **Primary completion:** 2027-12-31
- **Final completion:** 2027-12-31
- **Target enrollment:** 59 (ESTIMATED)
- **Last updated:** 2026-06-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07647068

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07647068, "Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07647068. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*