# Using Fenfluramine to Test the Serotonin Deficiency Theory of Depression

> **NCT07651293** · NA · NOT_YET_RECRUITING · sponsor: **Imperial College Healthcare NHS Trust** · enrollment: 46 (estimated)

## Conditions studied

- Depression - Major Depressive Disorder

## Interventions

- **DRUG:** Fenfluramine Hydrochloride
- **RADIATION:** [11C]Cimbi-36
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07651293
- **Lead sponsor:** Imperial College Healthcare NHS Trust
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07-01
- **Primary completion:** 2028-07
- **Final completion:** 2028-12
- **Target enrollment:** 46 (ESTIMATED)
- **Last updated:** 2026-06-16

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07651293

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07651293, "Using Fenfluramine to Test the Serotonin Deficiency Theory of Depression". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07651293. Licensed CC0.

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