# Bone Defects Reconstruction After Dentigerous Cyst Enucleation With Autogenous Demineralized Dentin Matrix- ADDM and Advanced Platelet-Rich Fibrin- A-PRF.

> **NCT07652216** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Jagiellonian University** · enrollment: 35 (actual)

## Conditions studied

- Impact Molar
- Mandible Cyst
- Bone Regeneration
- Platelet Rich Fibrin
- Dentigerous Cyst
- Dentin Matrix
- Autogenous Dentin Graft
- Demineralized Dentin Matrix
- Impacted Lower Third Molar
- Impacted Mandibular Third Molar

## Interventions

- **PROCEDURE:** Impacted third molar extraction
- **BIOLOGICAL:** Advanced Platelet-Rich Fibrin (A-PRF)
- **PROCEDURE:** Mandibular dentigerous cyst enucleation
- **BIOLOGICAL:** Autogenous Demineralized Dentin Matrix (ADDM)

## Key facts

- **NCT ID:** NCT07652216
- **Lead sponsor:** Jagiellonian University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2024-04-04
- **Primary completion:** 2026-12-01
- **Final completion:** 2027-04-01
- **Target enrollment:** 35 (ACTUAL)
- **Last updated:** 2026-06-23


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07652216

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07652216, "Bone Defects Reconstruction After Dentigerous Cyst Enucleation With Autogenous Demineralized Dentin Matrix- ADDM and Advanced Platelet-Rich Fibrin- A-PRF.". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07652216. Licensed CC0.

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