# A Phase II Observational Clinical Study on the Relationship Between Cerebrospinal Fluid Drug Concentration and Efficacy of Trastuzumab Deruxtecan in Central Nervous System Metastatic Breast Cancer

> **NCT07653893** · — · RECRUITING · sponsor: **Fudan University** · enrollment: 60 (estimated)

## Conditions studied

- Central Nervous System (CNS) Metastases
- Breast Cancer

## Interventions

- **OTHER:** No Interventions

## Key facts

- **NCT ID:** NCT07653893
- **Lead sponsor:** Fudan University
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2025-06-11
- **Primary completion:** 2027-06
- **Final completion:** 2028-06
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2026-06-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07653893

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07653893, "A Phase II Observational Clinical Study on the Relationship Between Cerebrospinal Fluid Drug Concentration and Efficacy of Trastuzumab Deruxtecan in Central Nervous System Metastatic Breast Cancer". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07653893. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*