# The MTA Effect on Healing and Biomarkers in Endo-Perio Lesions

> **NCT07653997** · NA · COMPLETED · sponsor: **Istanbul Medipol University Hospital** · enrollment: 120 (actual)

## Conditions studied

- Endodontic-Periodontal Lesions
- Apical Periodontitis
- Periapical Disease

## Interventions

- **PROCEDURE:** Root Canal Treatment with MTA Apical Plug
- **PROCEDURE:** Root Canal Treatment with Resin-Based Sealer (AH Plus)
- **PROCEDURE:** Periodontal Therapy (Scaling and Root Planing)
- **OTHER:** Gingival Crevicular Fluid Sampling

## Key facts

- **NCT ID:** NCT07653997
- **Lead sponsor:** Istanbul Medipol University Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2024-03-20
- **Primary completion:** 2025-04-10
- **Final completion:** 2026-04-20
- **Target enrollment:** 120 (ACTUAL)
- **Last updated:** 2026-06-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07653997

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07653997, "The MTA Effect on Healing and Biomarkers in Endo-Perio Lesions". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07653997. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*