# OBSERVE: A Pilot Study Of Omission Of Brain Metastasis Stereotactic Radiosurgery Following Resection With CNS-Active Systemic Therapy

> **NCT07655583** · PHASE1 · RECRUITING · sponsor: **M.D. Anderson Cancer Center** · enrollment: 20 (estimated)

## Conditions studied

- Brain Metastasis
- Stereotactic Radiosurgery
- Resection
- Systemic Therapy

## Interventions

- **OTHER:** Systemic therapy

## Key facts

- **NCT ID:** NCT07655583
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-05-27
- **Primary completion:** 2028-06-30
- **Final completion:** 2030-06-30
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2026-09-15


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07655583

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07655583, "OBSERVE: A Pilot Study Of Omission Of Brain Metastasis Stereotactic Radiosurgery Following Resection With CNS-Active Systemic Therapy". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07655583. Licensed CC0.

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