# A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD)

> **NCT07656415** · PHASE3 · RECRUITING · sponsor: **Agios Pharmaceuticals, Inc.** · enrollment: 159 (estimated)

## Conditions studied

- Sickle Cell Disease

## Interventions

- **DRUG:** Mitapivat Matched Placebo
- **DRUG:** Mitapivat

## Key facts

- **NCT ID:** NCT07656415
- **Lead sponsor:** Agios Pharmaceuticals, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-07-21
- **Primary completion:** 2029-08
- **Final completion:** 2030-08
- **Target enrollment:** 159 (ESTIMATED)
- **Last updated:** 2026-09-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07656415

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07656415, "A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD)". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07656415. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*