# Duo: A Phase IIIb Individual-Level Randomized Controlled Trial of an Integrated Strategy

> **NCT07658976** · PHASE3 · NOT_YET_RECRUITING · sponsor: **HIV Prevention Trials Network** · enrollment: 400 (estimated)

## Conditions studied

- HIV Infection
- Sexually Transmitted Infection

## Interventions

- **DRUG:** HIV PrEP - choice of F/TDF, F/TAF, or CAB-LA
- **DRUG:** STI PEP - Doxycycline as Doxy-PEP
- **BEHAVIORAL:** 3P mHealth package
- **BEHAVIORAL:** Handout about HIV PrEP options available at the site
- **BEHAVIORAL:** Standard-of-care HIV PrEP counseling from qualified study staff

## Key facts

- **NCT ID:** NCT07658976
- **Lead sponsor:** HIV Prevention Trials Network
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09-01
- **Primary completion:** 2029-09-01
- **Final completion:** 2029-09-01
- **Target enrollment:** 400 (ESTIMATED)
- **Last updated:** 2026-06-22

## Collaborators

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- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07658976

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07658976, "Duo: A Phase IIIb Individual-Level Randomized Controlled Trial of an Integrated Strategy". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07658976. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*