# Optimizing Anticoagulation in Pregnancies With Mechanical Heart Valves

> **NCT07658989** · NA · RECRUITING · sponsor: **Mount Sinai Hospital, Canada** · enrollment: 100 (estimated)

## Conditions studied

- Pregnancy
- Prosthetic Heart Valve
- Anticoagulant Therapy

## Interventions

- **DRUG:** LMWH and LDA
- **OTHER:** Vitamin K antagonists (e.g warfarin)+/- LDA
- **OTHER:** Sequential therapy +/- LDA

## Key facts

- **NCT ID:** NCT07658989
- **Lead sponsor:** Mount Sinai Hospital, Canada
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-05-26
- **Primary completion:** 2030-01
- **Final completion:** 2030-12
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-06-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07658989

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07658989, "Optimizing Anticoagulation in Pregnancies With Mechanical Heart Valves". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07658989. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*