NgFUS NIVO: NeuroNavigation-Guided Focused Ultrasound With Nivolumab in Relapsed and Progressive DMG and Other High Grade Brain Tumors

NCT07664176 · clinicaltrials.gov ↗

PHASE1

Phase

RECRUITING

Status

30

Enrollment

OTHER

Sponsor class

Conditions

Diffuse Midline Glioma or Diffuse Intrinsic Pontine Glioma
High Grade Gliomas
Medulloblastoma Recurrent
Ependymoma Recurrent
Atypical Teratoid/Rhabdoid Tumor (ATRT) of the CNS
Brain Tumor Recurrent

Interventions

DEVICE: NeuroNavigation-Guided Focused Ultrasound (NgFUS)
DRUG: Lumason
DRUG: Nivolumab

Sponsor

Children's National Research Institute