# Effect of Platelet-Rich Plasma on Eardrum Healing and Hearing After Tympanoplasty in Adults

> **NCT07664319** · NA · COMPLETED · sponsor: **Ebubekir Toprak** · enrollment: 48 (actual)

## Conditions studied

- Chronic Otitis Media Tympanic Membrane Perforation

## Interventions

- **BIOLOGICAL:** Autologous platelet-rich plasma (PRP)-impregnated Spongostan
- **OTHER:** Dry Spongostan (absorbable gelatin sponge)

## Key facts

- **NCT ID:** NCT07664319
- **Lead sponsor:** Ebubekir Toprak
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-04-01
- **Primary completion:** 2023-06-30
- **Final completion:** 2023-08-31
- **Target enrollment:** 48 (ACTUAL)
- **Last updated:** 2026-06-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07664319

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07664319, "Effect of Platelet-Rich Plasma on Eardrum Healing and Hearing After Tympanoplasty in Adults". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07664319. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*