# Algorithm-Based Timing of Delivery Using the sFlt-1/PlGF Ratio in Early-Onset Severe Preeclampsia. (MAP 2 Study : Management Based on Angiogenic Markers in Preeclampsia 2 Study )

> **NCT07665112** · NA · NOT_YET_RECRUITING · sponsor: **Hospital Clinic of Barcelona** · enrollment: 386 (estimated)

## Conditions studied

- Severe Preeclampsia

## Interventions

- **OTHER:** sFlt-1/PlGF ratio-guided management algorithm
- **OTHER:** Usual Care

## Key facts

- **NCT ID:** NCT07665112
- **Lead sponsor:** Hospital Clinic of Barcelona
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07-01
- **Primary completion:** 2029-09-30
- **Final completion:** 2029-12-31
- **Target enrollment:** 386 (ESTIMATED)
- **Last updated:** 2026-06-24

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07665112

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07665112, "Algorithm-Based Timing of Delivery Using the sFlt-1/PlGF Ratio in Early-Onset Severe Preeclampsia. (MAP 2 Study : Management Based on Angiogenic Markers in Preeclampsia 2 Study )". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07665112. Licensed CC0.

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