# APG-157 in Locally Advanced Head and Neck Squamous Cell Carcinoma

> **NCT07667296** · PHASE3 · NOT_YET_RECRUITING · sponsor: **Aveta Biomics, Inc.** · enrollment: 826 (estimated)

## Conditions studied

- Head and Neck Cancer
- Head and Neck (HNSCC)
- Oropharyngeal
- Oral Cavity
- Oral Cavity Carcinoma
- Oropharynx Squamous Cell Carcinoma
- Oral Cavity Squamous Cell Carcinoma

## Interventions

- **DRUG:** APG-157
- **PROCEDURE:** Surgery
- **RADIATION:** Radiation/Chemotherapy
- **RADIATION:** Radiation/Chemotherapy

## Key facts

- **NCT ID:** NCT07667296
- **Lead sponsor:** Aveta Biomics, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07
- **Primary completion:** 2031-12
- **Final completion:** 2032-12
- **Target enrollment:** 826 (ESTIMATED)
- **Last updated:** 2026-07-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07667296

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07667296, "APG-157 in Locally Advanced Head and Neck Squamous Cell Carcinoma". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07667296. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*