# A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department

> **NCT07667621** · PHASE1 · NOT_YET_RECRUITING · sponsor: **University of South Florida** · enrollment: 100 (estimated)

## Conditions studied

- Migraine
- Migraine Disease
- Migraine in Adults
- Migraine Headache
- Acute Migraine
- Migraine Without Aura
- Migraine With Aura

## Interventions

- **DRUG:** Rimegepant
- **DRUG:** Zavegepant

## Key facts

- **NCT ID:** NCT07667621
- **Lead sponsor:** University of South Florida
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07
- **Primary completion:** 2027-07
- **Final completion:** 2027-08
- **Target enrollment:** 100 (ESTIMATED)
- **Last updated:** 2026-06-25

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07667621

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07667621, "A Prospective, Open-Label Study Evaluating the Effectiveness of Gepants for Acute Treatment of Migraine in the Emergency Department". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07667621. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
