# A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

> **NCT07668414** · PHASE3 · RECRUITING · sponsor: **Novo Nordisk A/S** · enrollment: 650 (estimated)

## Conditions studied

- Overweight
- Obesity

## Interventions

- **DRUG:** Zenagamtide
- **DRUG:** Semaglutide
- **DRUG:** Placebo (matched to semaglutide)
- **DRUG:** Placebo (matched to zenagamtide)

## Key facts

- **NCT ID:** NCT07668414
- **Lead sponsor:** Novo Nordisk A/S
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-09-22
- **Primary completion:** 2028-10-10
- **Final completion:** 2028-10-10
- **Target enrollment:** 650 (ESTIMATED)
- **Last updated:** 2026-09-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07668414

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07668414, "A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide". Retrieved via MORVS 2026-10-22 from https://api.morvs.ai/clinical/NCT07668414. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*