# PIEZO-101 First-in-Human Safety and Proof-of-Concept Study

> **NCT07671027** · EARLY_PHASE1 · NOT_YET_RECRUITING · sponsor: **Piezo Therapeutics, Inc.** · enrollment: 8 (estimated)

## Conditions studied

- Skin Aging
- Wrinkles in Decolletage
- Wrinkles in Left Knee
- Left Knee Skin Laxity
- Décolleté Wrinkles

## Interventions

- **BIOLOGICAL:** PIEZO-101
- **DEVICE:** Piezopen
- **OTHER:** Sterile Saline (0.9% NaCl)

## Key facts

- **NCT ID:** NCT07671027
- **Lead sponsor:** Piezo Therapeutics, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09
- **Primary completion:** 2027-08
- **Final completion:** 2027-08
- **Target enrollment:** 8 (ESTIMATED)
- **Last updated:** 2026-06-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07671027

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07671027, "PIEZO-101 First-in-Human Safety and Proof-of-Concept Study". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07671027. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*