# Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty

> **NCT07672301** · PHASE1,PHASE2 · RECRUITING · sponsor: **University of Chicago** · enrollment: 150 (estimated)

## Conditions studied

- Total Knee Arthroplasty (TKA)

## Interventions

- **COMBINATION_PRODUCT:** Total IntraVenous Anesthesia (TIVA)
- **COMBINATION_PRODUCT:** Spinal-Block
- **DEVICE:** Electroencephalogram (EEG)

## Key facts

- **NCT ID:** NCT07672301
- **Lead sponsor:** University of Chicago
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-03-11
- **Primary completion:** 2027-06
- **Final completion:** 2028-06
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2026-06-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07672301

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07672301, "Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07672301. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*