# Effect of Platelet-Rich Fibrin on Postoperative Pain, Trismus, and Edema After Mandibular Third Molar Surgery

> **NCT07672951** · NA · COMPLETED · sponsor: **PAEC General Hospital, Islamabad** · enrollment: 134 (actual)

## Conditions studied

- Impacted Mandibular Third Molar
- Postoperative Pain
- Trismus
- Edema Face

## Interventions

- **BIOLOGICAL:** Platelet-rich fibrin (PRF)
- **DEVICE:** Sterile Absorbable Gelatin Sponge

## Key facts

- **NCT ID:** NCT07672951
- **Lead sponsor:** PAEC General Hospital, Islamabad
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2025-12-09
- **Primary completion:** 2026-05-16
- **Final completion:** 2026-05-22
- **Target enrollment:** 134 (ACTUAL)
- **Last updated:** 2026-06-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07672951

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07672951, "Effect of Platelet-Rich Fibrin on Postoperative Pain, Trismus, and Edema After Mandibular Third Molar Surgery". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07672951. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*