# New Biomarkers for Organ Viability Assessment During Hypothermic Machine Perfusion in Liver Transplantation: the Role of Extemporaneous Histological Examination.

> **NCT07674394** · NA · NOT_YET_RECRUITING · sponsor: **The Mediterranean Institute for Transplantation and Advanced Specialized Therapies** · enrollment: 150 (estimated)

## Conditions studied

- Liver Transplantation (LT)
- Early Allograft Dysfunction
- Primary Non-function
- Ischemia-Reperfusion Injury

## Interventions

- **PROCEDURE:** Hypothermic Oxygenated Machine Perfusion (HOPE/D-HOPE)

## Key facts

- **NCT ID:** NCT07674394
- **Lead sponsor:** The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07
- **Primary completion:** 2028-12
- **Final completion:** 2029-06
- **Target enrollment:** 150 (ESTIMATED)
- **Last updated:** 2026-06-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07674394

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07674394, "New Biomarkers for Organ Viability Assessment During Hypothermic Machine Perfusion in Liver Transplantation: the Role of Extemporaneous Histological Examination.". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07674394. Licensed CC0.

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