# Efficacy of Lymphatic-Venous Anastomosis Plus Donepezil Versus Donepezil Alone for Alzheimer's Disease

> **NCT07680660** · NA · NOT_YET_RECRUITING · sponsor: **Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University** · enrollment: 216 (estimated)

## Conditions studied

- Alzheimer s Disease

## Interventions

- **PROCEDURE:** Cervical lymph vessel/node-venous anastomosis surgery combined with oral donepezil
- **DRUG:** Oral treatment with donepezil

## Key facts

- **NCT ID:** NCT07680660
- **Lead sponsor:** Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07-15
- **Primary completion:** 2028-09-30
- **Final completion:** 2029-03-31
- **Target enrollment:** 216 (ESTIMATED)
- **Last updated:** 2026-07-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07680660

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07680660, "Efficacy of Lymphatic-Venous Anastomosis Plus Donepezil Versus Donepezil Alone for Alzheimer's Disease". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07680660. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*