# Escalating Cycle 1 Dose of Lu-177-PSMA-617 for the Treatment of Metastatic Castration Resistant Prostate Cancer

> **NCT07682649** · PHASE1 · NOT_YET_RECRUITING · sponsor: **University of Michigan Rogel Cancer Center** · enrollment: 20 (estimated)

## Conditions studied

- Metastatic Castration-Resistant Prostate Carcinoma
- Stage IVB Prostate Cancer AJCC v8

## Interventions

- **PROCEDURE:** Biospecimen Collection
- **PROCEDURE:** Computed Tomography
- **OTHER:** Gallium Ga 68 Gozetotide
- **DRUG:** Lutetium Lu 177 Vipivotide Tetraxetan
- **DEVICE:** Positron Emission Tomography
- **OTHER:** Questionnaire Administration
- **DEVICE:** Single Photon Emission Computed Tomography
- **OTHER:** Technetium Tc-99m Sulfur Colloid

## Key facts

- **NCT ID:** NCT07682649
- **Lead sponsor:** University of Michigan Rogel Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-08-01
- **Primary completion:** 2027-08
- **Final completion:** 2031-08
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2026-07-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07682649

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07682649, "Escalating Cycle 1 Dose of Lu-177-PSMA-617 for the Treatment of Metastatic Castration Resistant Prostate Cancer". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07682649. Licensed CC0.

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