# Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis

> **NCT07682662** · PHASE4 · NOT_YET_RECRUITING · sponsor: **University of Mississippi Medical Center** · enrollment: 400 (estimated)

## Conditions studied

- Vaso-Occlusive Pain Episode in Sickle Cell Disease
- Sickle Cell Disease (SCD)

## Interventions

- **DRUG:** Standardized Low-dose bolus IV Ketamine within 30 minutes of arrival and every 1 hour as needed for max of 3 doses.
- **OTHER:** Standard Care (in control arm)

## Key facts

- **NCT ID:** NCT07682662
- **Lead sponsor:** University of Mississippi Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-08-01
- **Primary completion:** 2029-08-31
- **Final completion:** 2029-10-01
- **Target enrollment:** 400 (ESTIMATED)
- **Last updated:** 2026-07-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07682662

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07682662, "Low Dose Bolus Ketamine For Use In Sickle Cell Pain Crisis". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07682662. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*