# Hyaluronic Acid and I-PRF Mixture for TMJ Disc Displacement Management

> **NCT07683650** · NA · RECRUITING · sponsor: **Mansoura University** · enrollment: 72 (estimated)

## Conditions studied

- TMJ Disc Displacement With Reduction

## Interventions

- **PROCEDURE:** 18 joints that receive arthrocentesis using 100 ml of ringer lactate solution
- **PROCEDURE:** Arthrocentesis followed by hyaluronic acid injection
- **PROCEDURE:** Arthrocentesis followed by injection of hyaluronic acid and betamethasone mixture
- **PROCEDURE:** Arthrocentesis followed by injection of hyaluronic acid and I-PRF mixture

## Key facts

- **NCT ID:** NCT07683650
- **Lead sponsor:** Mansoura University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-01-06
- **Primary completion:** 2026-12
- **Final completion:** 2027-02
- **Target enrollment:** 72 (ESTIMATED)
- **Last updated:** 2026-07-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07683650

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07683650, "Hyaluronic Acid and I-PRF Mixture for TMJ Disc Displacement Management". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07683650. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*