# A First-in-Human SAD/MAD Study to Evaluate Safety, Tolerability and PK of ENC0653 Ointment in Healthy Adult Subjects

> **NCT07684196** · PHASE1 · RECRUITING · sponsor: **EnnovaBio** · enrollment: 56 (estimated)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** Low Dose, 10%BSA
- **DRUG:** Low Dose, 20%BSA
- **DRUG:** Middle Dose, 20%BSA
- **DRUG:** High Dose, 20%BSA
- **DRUG:** Low Dose, 20%BSA
- **DRUG:** Middle Dose, 20%BSA
- **DRUG:** High Dose, 20%BSA
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07684196
- **Lead sponsor:** EnnovaBio
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-06-17
- **Primary completion:** 2026-10-01
- **Final completion:** 2026-12-30
- **Target enrollment:** 56 (ESTIMATED)
- **Last updated:** 2026-07-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07684196

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07684196, "A First-in-Human SAD/MAD Study to Evaluate Safety, Tolerability and PK of ENC0653 Ointment in Healthy Adult Subjects". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07684196. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*