# Pregnenolone for Cannabis Use Disorder and Depression

> **NCT07685964** · PHASE1,PHASE2 · NOT_YET_RECRUITING · sponsor: **University of Texas Southwestern Medical Center** · enrollment: 20 (estimated)

## Conditions studied

- Cannabis Use Disorder
- Major Depressive Disorder (MDD)

## Interventions

- **DRUG:** Pregnenolone

## Key facts

- **NCT ID:** NCT07685964
- **Lead sponsor:** University of Texas Southwestern Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09
- **Primary completion:** 2028-08
- **Final completion:** 2028-08
- **Target enrollment:** 20 (ESTIMATED)
- **Last updated:** 2026-07-06

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07685964

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07685964, "Pregnenolone for Cannabis Use Disorder and Depression". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07685964. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*