# ctDNA-Guided Intraventricular Therapy for CNS Malignancies

> **NCT07689721** · NA · NOT_YET_RECRUITING · sponsor: **Alireza Mansouri** · enrollment: 77 (estimated)

## Conditions studied

- Leptomeningeal Disease
- Glioblastoma
- Brain Metastases
- Non-Small Cell Lung Cancer
- Breast Cancer

## Interventions

- **DEVICE:** CSF ctDNA-Guided Clinical Management

## Key facts

- **NCT ID:** NCT07689721
- **Lead sponsor:** Alireza Mansouri
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2027-01-01
- **Primary completion:** 2030-07-01
- **Final completion:** 2032-01-01
- **Target enrollment:** 77 (ESTIMATED)
- **Last updated:** 2026-07-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07689721

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07689721, "ctDNA-Guided Intraventricular Therapy for CNS Malignancies". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07689721. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*