# Restrictive Fluid Management In Liver Transplantation (REFIL)

> **NCT07695363** · NA · RECRUITING · sponsor: **Centre hospitalier de l'Université de Montréal (CHUM)** · enrollment: 866 (estimated)

## Conditions studied

- Liver Transplantation (LT)
- End-stage Liver Disease (ESLD)

## Interventions

- **PROCEDURE:** Low splanchnic blood volume restrictive fluid management strategy
- **PROCEDURE:** Phlebotomy
- **PROCEDURE:** Optimized cardiac output liberal fluid management strategy

## Key facts

- **NCT ID:** NCT07695363
- **Lead sponsor:** Centre hospitalier de l'Université de Montréal (CHUM)
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-02-15
- **Primary completion:** 2030-11
- **Final completion:** 2031-11
- **Target enrollment:** 866 (ESTIMATED)
- **Last updated:** 2026-07-10

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07695363

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07695363, "Restrictive Fluid Management In Liver Transplantation (REFIL)". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07695363. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*