# Microneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for Melasma

> **NCT07696806** · PHASE4 · ENROLLING_BY_INVITATION · sponsor: **Sameh Sarsik** · enrollment: 80 (estimated)

## Conditions studied

- Melasma (Facial Melasma)

## Interventions

- **DRUG:** Metformin 30% Topical Lotion
- **DRUG:** Tranexamic Acid 0.5% Topical Solution
- **DRUG:** Modified Kligman's Formula
- **DRUG:** Normal Saline

## Key facts

- **NCT ID:** NCT07696806
- **Lead sponsor:** Sameh Sarsik
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2026-07-10
- **Primary completion:** 2027-06-30
- **Final completion:** 2027-08-30
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2026-07-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07696806

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07696806, "Microneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for Melasma". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07696806. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*