# RELIEVE-HFrEF TRIAL: REducing Lung congestIon Symptoms Using the v-wavE Shunt in adVancEd Heart Failure With Reduced EF

> **NCT07696975** · NA · NOT_YET_RECRUITING · sponsor: **V-Wave Ltd** · enrollment: 250 (estimated)

## Conditions studied

- Heart Failure and Reduced Ejection Fraction
- Heart Failure Chronic
- Heart Failure New York Heart Association Class III
- Heart Failure Congestive

## Interventions

- **DEVICE:** Implantation of the V-Wave Interatrial shunt
- **DEVICE:** Sham (no implant)

## Key facts

- **NCT ID:** NCT07696975
- **Lead sponsor:** V-Wave Ltd
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09-30
- **Primary completion:** 2029-03-31
- **Final completion:** 2031-09-30
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2026-07-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07696975

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07696975, "RELIEVE-HFrEF TRIAL: REducing Lung congestIon Symptoms Using the v-wavE Shunt in adVancEd Heart Failure With Reduced EF". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07696975. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*