# The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression

> **NCT07699445** · PHASE4 · RECRUITING · sponsor: **Massachusetts General Hospital** · enrollment: 25 (estimated)

## Conditions studied

- Bipolar Depression Depressed Phase
- Obesity & Overweight

## Interventions

- **DRUG:** Lumateperone 42 mg

## Key facts

- **NCT ID:** NCT07699445
- **Lead sponsor:** Massachusetts General Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-09-09
- **Primary completion:** 2028-01-31
- **Final completion:** 2028-07-31
- **Target enrollment:** 25 (ESTIMATED)
- **Last updated:** 2026-09-11

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07699445

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07699445, "The Effects of Lumateperone on Obesity and Physiologic Aging and Their Association With Antidepressant Response in Bipolar Depression". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07699445. Licensed CC0.

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