# The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline Anesthesia

> **NCT07699523** · NA · NOT_YET_RECRUITING · sponsor: **China-Japan Friendship Hospital** · enrollment: 120 (estimated)

## Conditions studied

- Depth of Anesthesia Monitoring
- BIS-EEG

## Interventions

- **DRUG:** Midazolam
- **DRUG:** Dexmedetomidine
- **DRUG:** Esketamine
- **DRUG:** Propofol
- **DRUG:** Remifentanil

## Key facts

- **NCT ID:** NCT07699523
- **Lead sponsor:** China-Japan Friendship Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-06-30
- **Primary completion:** 2027-06-30
- **Final completion:** 2027-12-30
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2026-07-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07699523

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07699523, "The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline Anesthesia". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07699523. Licensed CC0.

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