# Perioperative FLOT(D) With Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) in Esophageal Cancer

> **NCT07700420** · PHASE1 · RECRUITING · sponsor: **University of Texas Southwestern Medical Center** · enrollment: 15 (estimated)

## Conditions studied

- Gastro-esophageal Junction (GEJ) Cancer
- Esophagus Cancer

## Interventions

- **RADIATION:** PULSAR- Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy
- **DRUG:** FLOT (Fluorouracil+Leucovorin+Oxaliplatin+Docetaxel)(D)

## Key facts

- **NCT ID:** NCT07700420
- **Lead sponsor:** University of Texas Southwestern Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-08-28
- **Primary completion:** 2027-10-01
- **Final completion:** 2031-10-01
- **Target enrollment:** 15 (ESTIMATED)
- **Last updated:** 2026-09-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07700420

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07700420, "Perioperative FLOT(D) With Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy (PULSAR) in Esophageal Cancer". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07700420. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*