# Hypertonic Saline as a Final Flush and Post-Operative Pain After Single Visit Root Canal Treatment in Mandibular Premolar.

> **NCT07701551** · PHASE4 · NOT_YET_RECRUITING · sponsor: **Cairo University** · enrollment: 40 (estimated)

## Conditions studied

- Symptomatic Irreversible Pulpitis (SIP)

## Interventions

- **DRUG:** Normal (0.9%) saline
- **DRUG:** Hypertonic 3% saline

## Key facts

- **NCT ID:** NCT07701551
- **Lead sponsor:** Cairo University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-08-01
- **Primary completion:** 2027-01-01
- **Final completion:** 2027-01-01
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2026-07-14


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07701551

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07701551, "Hypertonic Saline as a Final Flush and Post-Operative Pain After Single Visit Root Canal Treatment in Mandibular Premolar.". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07701551. Licensed CC0.

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