# Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection

> **NCT07706686** · PHASE1 · RECRUITING · sponsor: **National Institute of Allergy and Infectious Diseases (NIAID)** · enrollment: 200 (estimated)

## Conditions studied

- Healthy Volunteers
- Dengue
- Human Challenge Trial

## Interventions

- **BIOLOGICAL:** rDEN2delta30-7169

## Key facts

- **NCT ID:** NCT07706686
- **Lead sponsor:** National Institute of Allergy and Infectious Diseases (NIAID)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-08-07
- **Primary completion:** 2028-11-03
- **Final completion:** 2029-05-03
- **Target enrollment:** 200 (ESTIMATED)
- **Last updated:** 2026-09-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07706686

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07706686, "Phase 1 Challenge Study Using rDEN2delta30-7169 to Evaluate Host-Pathogen Interactions in Primary, Homotypic, and Heterotypic Dengue Virus Infection". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07706686. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*