# This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients

> **NCT07707063** · PHASE4 · RECRUITING · sponsor: **Military Hospital of Tunis** · enrollment: 50 (estimated)

## Conditions studied

- Periodontitis
- Smokers
- Non Smokers
- Periodontal Disease

## Interventions

- **BIOLOGICAL:** Injectable Platelet-Rich Fibrin (I-PRF)
- **DEVICE:** Diode Laser Activation
- **DRUG:** Povidone-Iodine Irrigation (1%)
- **PROCEDURE:** Saline Irrigation (0.9%)
- **PROCEDURE:** Scaling and Root Planing

## Key facts

- **NCT ID:** NCT07707063
- **Lead sponsor:** Military Hospital of Tunis
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-05-25
- **Primary completion:** 2027-05-18
- **Final completion:** 2027-05-18
- **Target enrollment:** 50 (ESTIMATED)
- **Last updated:** 2026-07-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07707063

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07707063, "This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07707063. Licensed CC0.

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