# Cardiovascular Effects of Parathyroid Hormone Analogues in Chronic Hypoparathyroidism

> **NCT07707479** · — · ACTIVE_NOT_RECRUITING · sponsor: **National and Kapodistrian University of Athens** · enrollment: 210 (estimated)

## Conditions studied

- Chronic Hypoparathyroidism

## Interventions

- **DIAGNOSTIC_TEST:** Arterial stiffness in the aorta by measurement of pulse wave velocity
- **DIAGNOSTIC_TEST:** Central blood pressures and reflected waves in the aorta
- **DIAGNOSTIC_TEST:** Carotid and femoral intima-media thickness (IMT) and number of carotid or femoral plaques
- **DIAGNOSTIC_TEST:** Imaging of the sublingual microcirculation (GlycoCheck system)
- **DIAGNOSTIC_TEST:** Ankle-brachial index (ABI)
- **DIAGNOSTIC_TEST:** Fundoscopy
- **DIAGNOSTIC_TEST:** Cardiac Ultrasonography Study
- **DIAGNOSTIC_TEST:** Local shear stress in brachial and carotid artery
- **DIAGNOSTIC_TEST:** Peripheral and aortic office and ambulatory blood pressure
- **DIAGNOSTIC_TEST:** Circulating levels of myocardial biomarkers
- **DIAGNOSTIC_TEST:** Evaluation of Calcium metabolism

## Key facts

- **NCT ID:** NCT07707479
- **Lead sponsor:** National and Kapodistrian University of Athens
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2026-04-01
- **Primary completion:** 2027-04-01
- **Final completion:** 2028-12-31
- **Target enrollment:** 210 (ESTIMATED)
- **Last updated:** 2026-07-16

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07707479

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07707479, "Cardiovascular Effects of Parathyroid Hormone Analogues in Chronic Hypoparathyroidism". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07707479. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*