# Prenatal Blood Typing With Next Generation Sequencing (NGS) - an Implementation Study in HDFN (PREFAB)

> **NCT07715214** · NA · NOT_YET_RECRUITING · sponsor: **Karolinska University Hospital** · enrollment: 750 (estimated)

## Conditions studied

- Red Blood Cell Alloimmunization in Pregnancy
- HDFN
- Next Generation Sequencing (NGS)

## Interventions

- **DIAGNOSTIC_TEST:** NGS analysis for fetal red cell blood type in maternal plasma

## Key facts

- **NCT ID:** NCT07715214
- **Lead sponsor:** Karolinska University Hospital
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09-01
- **Primary completion:** 2028-12-31
- **Final completion:** 2030-12-31
- **Target enrollment:** 750 (ESTIMATED)
- **Last updated:** 2026-07-20

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07715214

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07715214, "Prenatal Blood Typing With Next Generation Sequencing (NGS) - an Implementation Study in HDFN (PREFAB)". Retrieved via MORVS 2026-10-21 from https://api.morvs.ai/clinical/NCT07715214. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*