# Pre-hepatectomy Rehabilitation in Obese MASLD-Complicated Living Liver Donors With Mazdutide (PRIME)

> **NCT07718126** · PHASE4 · RECRUITING · sponsor: **West China Hospital** · enrollment: 60 (estimated)

## Conditions studied

- Metabolic Dysfunction-Associated Steatohepatitis
- Hepatic Steatosis
- Living Liver Donors

## Interventions

- **DRUG:** Mazdutide
- **DRUG:** Placebo (Normal Saline)
- **BEHAVIORAL:** Lifestyle Optimization

## Key facts

- **NCT ID:** NCT07718126
- **Lead sponsor:** West China Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-09-01
- **Primary completion:** 2029-02-28
- **Final completion:** 2029-08-31
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2026-09-23

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07718126

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07718126, "Pre-hepatectomy Rehabilitation in Obese MASLD-Complicated Living Liver Donors With Mazdutide (PRIME)". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07718126. Licensed CC0.

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