# Childhood-onset Lupus Nephritis Initial Glucocorticoid-dose Harmonization Trial (LIGHT Trial)

> **NCT07719140** · PHASE4 · RECRUITING · sponsor: **Peking Union Medical College Hospital** · enrollment: 198 (estimated)

## Conditions studied

- Childhood-onset Systemic Lupus Erythematosus
- Lupus Nephritis (LN)

## Interventions

- **DRUG:** High-dose prednisone
- **DRUG:** Low-dose prednisone

## Key facts

- **NCT ID:** NCT07719140
- **Lead sponsor:** Peking Union Medical College Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2026-07
- **Primary completion:** 2028-09
- **Final completion:** 2029-03
- **Target enrollment:** 198 (ESTIMATED)
- **Last updated:** 2026-07-22

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07719140

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07719140, "Childhood-onset Lupus Nephritis Initial Glucocorticoid-dose Harmonization Trial (LIGHT Trial)". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07719140. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*