# Efficacy Comparison of 10-Day High-Dose Versus 14-Day Standard-Dose Vonoprazan Plus Amoxicillin in Helicobacter Pylori Eradication: A Multicenter Non-Inferiority Randomized Controlled Trial

> **NCT07720037** · PHASE4 · NOT_YET_RECRUITING · sponsor: **Shandong University** · enrollment: 232 (estimated)

## Conditions studied

- Helicobacter Infection
- Vonoprazan
- Amoxicillin

## Interventions

- **DRUG:** 10-day group
- **DRUG:** 14-day group

## Key facts

- **NCT ID:** NCT07720037
- **Lead sponsor:** Shandong University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-09-30
- **Primary completion:** 2026-09-30
- **Final completion:** 2028-05-30
- **Target enrollment:** 232 (ESTIMATED)
- **Last updated:** 2026-09-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07720037

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07720037, "Efficacy Comparison of 10-Day High-Dose Versus 14-Day Standard-Dose Vonoprazan Plus Amoxicillin in Helicobacter Pylori Eradication: A Multicenter Non-Inferiority Randomized Controlled Trial". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07720037. Licensed CC0.

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