# Human Cognition During Surgery: Stimulation-based and Cholinergic Modulation

> **NCT07721272** · EARLY_PHASE1 · NOT_YET_RECRUITING · sponsor: **University of Texas Southwestern Medical Center** · enrollment: 30 (estimated)

## Conditions studied

- Epilepsy
- Essential Tremor
- Seizures
- Memory Consolidation
- Memory Disorders
- Memory Replay
- Memory Encoding
- Cognitive Control
- Motor Abilities

## Interventions

- **DRUG:** Cobenfy KarXT pill (50/20 mg)
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT07721272
- **Lead sponsor:** University of Texas Southwestern Medical Center
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-10
- **Primary completion:** 2030-09
- **Final completion:** 2030-09
- **Target enrollment:** 30 (ESTIMATED)
- **Last updated:** 2026-07-23

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT07721272

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT07721272, "Human Cognition During Surgery: Stimulation-based and Cholinergic Modulation". Retrieved via MORVS 2026-10-20 from https://api.morvs.ai/clinical/NCT07721272. Licensed CC0.

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